Abstract

In medical chemistry, several quinoline compounds, whether synthetic or natural, are widely used. The present study's synthetic strategy is to synthesize 1,2- dihydroquinoline sulphonamide derivatives for antihelmintic activity and Cytotoxic Activity. The effective synthesis of sulfonamides with a 1,2-dihydroquinoline nucleus was the main goal of the research project. The reactions are conducted at a moderate temperature of 60-90 OC using the solvents methylene dichloride and tetrahydrofuran to produce final products with a high yield, short half-life, and high purity. This makes the processes environmentally benign. NMR, 13C NMR, and IR studies provided detailed characterizations of recently synthesized substances. The biological properties of the recently created compounds, such as their antibacterial and anti-inflammatory properties, were examined. All four of the compounds exhibited moderate cytotoxic activity when evaluated biologically.