The in Vitro Anti-Inflammatory and Antioxidant Activitites of the Bark Extracts from Castanea Mollissima in Vietnam
Abstract
Evaluation results of anti-inflammatory effects through the inhibition of NO production in RAW264.7 macrophages and antioxidant activity using the DPPH method of the crude extract (TK); fractional extracts: n-hexane (TKH), ethyl acetate (TKE) and methanol (TKM) of the bark Castanea mollissima in Vietnam as follows: The crude extract (TK) exhibited good anti-inflammatory and antioxidant activities in vitro with SC50 value of 29.13 µg/mL and IC50 value of 19.6 µg/mL, respectively. Fractionated extract, ethyl acetate (TKE) exhibited the best anti-inflammatory and antioxidant activities in vitro with SC50 value of 21.67 µg/ml and IC50 value of 17.4 µg/ml, respectively. The remaining fractions showed moderate and weak activity. The above results guide further research on chemical composition and anti-inflammatory and antioxidant activities in the future of the Castanea mollissima in Vietnam.
How to Cite This Article
Dam Thi Bich Hanh, Do Tien Lam, Dang Thi Thuy My, Ngu Truong Nhan (2025). The in Vitro Anti-Inflammatory and Antioxidant Activitites of the Bark Extracts from Castanea Mollissima in Vietnam . International Journal of Pharma Growth Research Review (IJPGARR), 2(2), 28-32. DOI: https://doi.org/10.54660/IJPGRR.2025.2.2.28-32